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Genetics of Ovarian Cancer

Only a small percentage of cancers involve inherited mutations that are passed from generation to generation. The majority of cancers can be attributed to acquired mutations. “Acquired” means that the mutations occur only in the tissue that is affected by cancer and that the changes are not present in all cells of the body. Acquired mutations are not inherited and are not passed down to our children.

Listed below are several genetic syndromes associated with an increased risk for ovarian cancer that require clinical care by a physician or other health care professional.

Hereditary Breast Ovarian Cancer Syndrome (BRCA1 / BRCA2)

Peutz-Jeghers Syndrome

Ovarian Cancer and Hereditary Nonpolyposis Colon Cancer (HNPCC)

Basal Cell Nevus Syndrome (Gorlin Syndrome)

Online Medical Reviewer: Louise Akin, RN, BSN
Online Medical Reviewer: Daphne Pierce-Smith, RN, MSN, FNP, CCRC
Last Annual Review Date: 10/7/2011
© 2000-2012 Krames StayWell, 780 Township Line Road, Yardley, PA 19067. All rights reserved. This information is not intended as a substitute for professional medical care. Always follow your healthcare professional's instructions.
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